Organosilyl Bloking Agents (Protective Agents) are widely used in organic synthesis especially in syntheses of drugs for most of them can be get easily , have a steady property , easy to use and can be get rid off in very mild conditions.
And in most of these cases, Silane Blocking Agent can protect/ deprotect functional groups selectively. It is has become a novel method for improving the process and enhancing the quality of the products in syntheses of drugs. Silane Blocking Agents (Protective Agents) are widely used in the syntheses including semi-synthesis and total synthesis of prostaglandins, 7-ADCA which is a intermediate of cephalosporin, Taxol which is a new anticance drug and Acylovir-a novel antivius drug.
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